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Decreased PPAR α aggravates proteinuria and renal damage by causing mitochondrial dysfunction and fatty acid buildup, which in turn increases podocyte death[34]

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Its genome is a circular, partially double-stranded DNA, which encodes four overlapping open reading frames: C (core, HbcAg), X (HBx), P (DNA polymerase) and S (surface antigen, HbsAg)